Antifungal Therapy

Antifungal photodynamic therapy.

In photodynamic antimicrobial chemotherapy (PACT), a combination of a sensitising drug and visible light causes selective destruction of microbial cells. The ability of light-drug combinations to kill microorganisms has been known for over 100 years. However, it is only recently with the beginning of the search for alternative treatments for antibiotic-resistant pathogens that the phenomenon ha...

Combination antifungal therapy.

Combination Antifungal Therapy Melissa D. Johnson,* Conan MacDougall, Luis Ostrosky-Zeichner, John R. Perfect, and John H. Rex Departments of Medicine, and Pharmacy, Duke University Medical Center, Durham, and Campbell University School of Pharmacy, Buies Creek, North Carolina; Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Re-emerging Pat...

The future of antifungal therapy.

Introduction The vision of the future is often induced and facilitated by the study of the past. The historian not only collects material to gain information of the past but many historians try to find general rules about the course of history, a formula which describes the movement of events in the past as well as in the future. An example of this is the investigation on the increasing number ...

New Horizons in Antifungal Therapy

Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics. Some of these studies have resulted in the identification of novel compounds that act against these pathways and also demonstrate potent antifungal activity. However, considerable effort is...

advances in antifungal therapy